Benign nocturnal alternating hemiplegia of childhood: two cases with positive evolution

Brain Dev. 2011 Jun;33(6):525-9. doi: 10.1016/j.braindev.2010.08.008. Epub 2010 Sep 2.

Abstract

Benign nocturnal alternating hemiplegia (BNAH) of childhood is distinct from the classic form of malignant alternating hemiplegia of childhood [1]. It is characterized by hemiplegic attacks occurring exclusively during sleep [2]. It can be misdiagnosed as migraine, nocturnal frontal lobe epilepsy, benign rolandic epilepsy, Panayiotopoulos syndrome, or sleep-related movement disorder [1-4]. Only nine patients have been described to date, with typically, a normal development [1,5-7]. In order to insist about the benignity of the affection, we report two cases: a new three-year-old boy suffering from BNAH and a patient already published to show positive evolution at fourteen years of age. BNAH is a rare disorder but may be underdiagnosed. Making an early diagnosis can help to describe to the parents the good prognosis without treatment.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Child, Preschool
  • Disease Progression
  • Hemiplegia / diagnosis*
  • Hemiplegia / physiopathology*
  • Humans
  • Male
  • Sleep Wake Disorders / diagnosis*
  • Sleep Wake Disorders / physiopathology*

Supplementary concepts

  • Alternating hemiplegia of childhood