Prolonged deferral of antiretroviral therapy in the SAPIT trial: did we need a clinical trial to tell us that this would increase mortality?

MeSH terms

• AIDS-Related Opportunistic Infections / microbiology
• Anti-Bacterial Agents / therapeutic use*
• Anti-Retroviral Agents / administration & dosage*
• CD4 Lymphocyte Count
• Clinical Trials as Topic / ethics*
• Drug Administration Schedule
• HIV Infections / drug therapy*
• HIV Infections / mortality*
• Humans
• Immune Reconstitution Inflammatory Syndrome
• South Africa / epidemiology
• Therapeutic Equipoise
• Tuberculosis / drug therapy*
• Tuberculosis / mortality