Role of positron emission tomography (PET) in head and neck cancer

Eur Ann Otorhinolaryngol Head Neck Dis. 2010 Mar;127(1):40-5. doi: 10.1016/j.anorl.2010.02.010. Epub 2010 Mar 25.

Abstract

F-18 fluorodeoxyglucose positron emission tomography is now part of the initial stage III and IV cancer work-up and each time that metastasis or the presence of a second cancer is suspected that may contraindicate major surgery. Similarly, this exam should be undertaken when the conventional work-up is negative but there is isolated metastatic adenopathy. In therapeutic follow-up, a 3- or 4-month delay must be respected to prevent false-positive exams caused by inflammation. Although FDG-PET seems very promising in determining target volumes in radiotherapy, its implementation raises a number of problems that can only be resolved through the collaboration of all of the different specialists.

Publication types

  • Review

MeSH terms

  • Adult
  • Fluorodeoxyglucose F18
  • Humans
  • Image Processing, Computer-Assisted*
  • Imaging, Three-Dimensional*
  • Lymphatic Metastasis / diagnostic imaging
  • Lymphatic Metastasis / pathology
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Neoplasms, Second Primary / diagnostic imaging
  • Neoplasms, Second Primary / pathology
  • Neoplasms, Second Primary / radiotherapy
  • Neoplasms, Second Primary / surgery
  • Otorhinolaryngologic Neoplasms / diagnostic imaging*
  • Otorhinolaryngologic Neoplasms / pathology
  • Otorhinolaryngologic Neoplasms / radiotherapy
  • Otorhinolaryngologic Neoplasms / surgery
  • Positron-Emission Tomography*
  • Radiotherapy Planning, Computer-Assisted
  • Treatment Outcome

Substances

  • Fluorodeoxyglucose F18