Internal target volume defined by contrast-enhanced 4D-CT scan in unresectable pancreatic tumour: evaluation and reproducibility

Giovanni Mauro Cattaneo; Paolo Passoni; Giulia Sangalli; Najla Slim; Barbara Longobardi; Pietro Mancosu; Valentino Bettinardi; Nadia Di Muzio; Riccardo Calandrino

doi:10.1016/j.radonc.2010.08.007

Internal target volume defined by contrast-enhanced 4D-CT scan in unresectable pancreatic tumour: evaluation and reproducibility

Radiother Oncol. 2010 Dec;97(3):525-9. doi: 10.1016/j.radonc.2010.08.007. Epub 2010 Sep 7.

Authors

Giovanni Mauro Cattaneo¹, Paolo Passoni, Giulia Sangalli, Najla Slim, Barbara Longobardi, Pietro Mancosu, Valentino Bettinardi, Nadia Di Muzio, Riccardo Calandrino

Affiliation

¹ Medical Physics Department, San Raffaele Scientific Institute, Milano, Italy. [email protected]

PMID: 20826027
DOI: 10.1016/j.radonc.2010.08.007

Abstract

We compared customized ITVs obtained with CE-4D-CT imaging (ITV(4D)) with a population-based (ITV(PBC)) in 29 patients (PTs) and evaluated the intra-observer ITV delineation reproducibility in 5 PTs with unresectable pancreatic ductal adenocarcinoma (PDA). The ITV(PBC) was quite different from the ITV(4D), with under/over estimation of volume. Intra-observer volume delineation variability on CE-4D-CT and on a single-phase CE-CT were similar (27.6% vs 24.9%).

Published by Elsevier Ireland Ltd.

MeSH terms

Adult
Aged
Aged, 80 and over
Carcinoma, Pancreatic Ductal / diagnostic imaging*
Carcinoma, Pancreatic Ductal / radiotherapy*
Contrast Media*
Female
Four-Dimensional Computed Tomography*
Humans
Male
Middle Aged
Observer Variation
Pancreatic Neoplasms / diagnostic imaging*
Pancreatic Neoplasms / radiotherapy*
Radiotherapy Planning, Computer-Assisted
Reproducibility of Results
Respiration
Triiodobenzoic Acids*
Tumor Burden

Substances

Contrast Media
Triiodobenzoic Acids
iodixanol