Willingness of breast cancer survivors to participate in a randomized controlled trial of digital mammography with or without MRI as breast cancer surveillance: a feasibility study

Daphne Tsoi; Claire Holloway; Louise Bordeleau; Christine Brezden-Masley; Petrina Causer; Ellen Warner

doi:10.1016/j.breast.2010.08.006

Willingness of breast cancer survivors to participate in a randomized controlled trial of digital mammography with or without MRI as breast cancer surveillance: a feasibility study

Breast. 2011 Feb;20(1):96-8. doi: 10.1016/j.breast.2010.08.006. Epub 2010 Sep 9.

Authors

Daphne Tsoi¹, Claire Holloway, Louise Bordeleau, Christine Brezden-Masley, Petrina Causer, Ellen Warner

Affiliation

¹ Department of Medical Oncology, Sunnybrook Odette Cancer Centre, The University of Toronto, 2075 Bayview Ave., Toronto, Ontario, Canada. [email protected]

PMID: 20829043
DOI: 10.1016/j.breast.2010.08.006

Abstract

Breast MRI is often used for surveillance of breast cancer (BC) survivors despite the lack of evidence in this population. We surveyed younger BC survivors to evaluate their willingness to participate in a randomized controlled trial (RCT) of annual digital mammography with or without MRI. Median age of the 348 participants was 51 years; 45% had undergone diagnostic MRI. 22% continued to have surveillance MRI. 58% agreed to consider participating in the proposed RCT; 16% remained neutral. An RCT of MRI surveillance for BC survivors <age 60 is still feasible at centres where annual MRI is not yet routinely recommended.

Publication types

Multicenter Study

MeSH terms

Adult
Breast Neoplasms / diagnosis*
Breast Neoplasms / diagnostic imaging
Feasibility Studies
Female
Humans
Magnetic Resonance Imaging*
Mammography*
Middle Aged
Neoplasm Recurrence, Local / diagnosis*
Neoplasm Recurrence, Local / diagnostic imaging
Patient Participation
Randomized Controlled Trials as Topic*
Survivors / statistics & numerical data*