Intracavitary voriconazole for the treatment of hemoptysis complicating Pseudallescheria angusta pulmonary mycetomas in fibrocystic sarcoidosis

Med Mycol. 2011 Feb;49(2):198-201. doi: 10.3109/13693786.2010.512619. Epub 2010 Sep 10.

Abstract

Pulmonary mycetomas often occur in fibrocystic sarcoidosis. When this condition is complicated by hemoptysis, definitive surgery is usually precluded because of poor lung function. Intracavitary antifungal therapy has been described for the treatment of symptomatic pulmonary mycetomas. We report the first use of intracavitary voriconazole in the management of a Pseudallescheria angusta pulmonary mycetoma complicated by hemoptysis in a patient with fibrocystic sarcoidosis and renal transplant.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antifungal Agents / administration & dosage*
  • Hemoptysis / diagnosis*
  • Hemoptysis / drug therapy
  • Hemoptysis / microbiology
  • Humans
  • Immunocompromised Host
  • Kidney Transplantation
  • Lung Diseases, Fungal / complications
  • Lung Diseases, Fungal / diagnosis*
  • Lung Diseases, Fungal / drug therapy
  • Lung Diseases, Fungal / microbiology
  • Male
  • Mycetoma / complications
  • Mycetoma / diagnosis*
  • Mycetoma / drug therapy
  • Mycetoma / microbiology
  • Pseudallescheria / isolation & purification*
  • Pyrimidines / administration & dosage*
  • Sarcoidosis / complications*
  • Triazoles / administration & dosage*
  • Voriconazole

Substances

  • Antifungal Agents
  • Pyrimidines
  • Triazoles
  • Voriconazole