Case report of MR perfusion imaging in sinking skin flap syndrome: growing evidence for hemodynamic impairment

BMC Neurol. 2010 Sep 11:10:80. doi: 10.1186/1471-2377-10-80.

Abstract

Background: The syndrome of the sinking skin flap (SSSF) with delayed sensorimotor deficits after craniectomy is not well known and often neglected. Among various postulated causes, there is evidence that disturbed brain perfusion may be related to the observed symptoms, and that cranioplasty reliably alleviates these symptoms. We report a case of sinking skin flap syndrome (SSFS) with recovery from neurological sensorimotor deficits after cranioplasty correlated with pre- and postsurgical MR brain perfusion studies.

Case presentation: A 42-year-old woman presented with slowly progressive sensorimotor paresis of her left arm after decompressive extensive craniectomy due to subarachnoid hemorrhage four months ago. Her right cranium showed a "sinking skin flap". After cranioplastic repair of her skull defect, the patient fully recovered from her symptoms. Before cranioplasty, reduced brain perfusion in the right central cortical region was observed in MR-perfusion images. After cranioplasty, a marked increase in brain perfusion was observed which correlated with objective clinical recovery.

Conclusion: There is increasing evidence that impaired blood flow is responsible for delayed motor deficits in patients with sinking skin flap syndrome in the area of compressed brain regions. Symptoms should be evaluated by brain perfusion imaging complementing surgical decision-making.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain / blood supply*
  • Cerebrovascular Circulation
  • Craniotomy*
  • Decompressive Craniectomy / adverse effects*
  • Female
  • Hemodynamics
  • Humans
  • Magnetic Resonance Imaging
  • Paresis / etiology
  • Paresis / surgery
  • Paresthesia / etiology
  • Paresthesia / surgery
  • Perfusion Imaging
  • Subarachnoid Hemorrhage / surgery
  • Surgical Flaps / adverse effects*