Abstract
New multivalent RGD-containing macromolecules were designed by exploiting two orthogonal chemoselective ligations. They were next applied to a competitive cell adhesion assay and used for the non invasive optical imaging of tumour in small animals.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Animals
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Biological Assay
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Cell Adhesion / drug effects
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Cell Line
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Chemistry, Organic / methods*
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Chromatography, High Pressure Liquid
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Humans
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Mice
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Molecular Sequence Data
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Oligopeptides / chemical synthesis*
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Oligopeptides / chemistry
Substances
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Oligopeptides
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arginyl-glycyl-aspartic acid