Abstract
C(1)-symmetric isoquinoline-based chiral diaminocarbene ligands (MIQ) have been developed to block three quadrants of the metal coordination sphere, complementing C(2)-symmetric biisoquinoline-based ligands (BIQ). MIQ-Cu complexes catalyzed conjugate borylation of various α,β-unsaturated amides in good yields (82-99%) and enantioselectivities (75-87% ee).
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Amides / chemistry
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Catalysis
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Heterocyclic Compounds / chemistry
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Isoquinolines / chemistry*
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Ligands
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Methane / analogs & derivatives*
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Methane / chemistry
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Models, Molecular
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Molecular Structure
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Stereoisomerism
Substances
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Amides
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Heterocyclic Compounds
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Isoquinolines
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Ligands
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carbene
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isoquinoline
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Methane