Abstract
Acinetobacter lwoffii, a species whose natural habitat is the human skin, intrinsically possesses a chromosomal gene encoding a carbapenem-hydrolyzing class D β-lactamase, OXA-134. This species may therefore constitute a reservoir for carbapenemase genes that may spread among other Acinetobacter species.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acinetobacter / drug effects
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Acinetobacter / enzymology*
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Acinetobacter / genetics
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Amino Acid Sequence
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Anti-Bacterial Agents / pharmacology
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Bacterial Proteins / chemistry
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Bacterial Proteins / classification
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Bacterial Proteins / metabolism*
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Carbapenems / metabolism*
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Escherichia coli / drug effects
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Escherichia coli / genetics
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Microbial Sensitivity Tests
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Molecular Sequence Data
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Phylogeny
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Sequence Homology, Amino Acid
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beta-Lactamases / chemistry
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beta-Lactamases / classification
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beta-Lactamases / metabolism*
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beta-Lactams / pharmacology
Substances
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Anti-Bacterial Agents
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Bacterial Proteins
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Carbapenems
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beta-Lactams
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beta-Lactamases