Characteristics of Chronic Pain and Its Impact on Quality of Life of Patients With HTLV-1-associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP)

Clin J Pain. 2011 Feb;27(2):131-5. doi: 10.1097/AJP.0b013e3181f195d3.

Abstract

Objectives: we describe the prevalence of chronic pain and their characteristics in 43 consecutive patients presenting with human T-lymphotropic virus Type I (HTLV-1) associated myelopathy (HAM) /tropical spastic paraparesis in Salvador, Brazil.

Methods: in this cross-sectional study, we included 43 consecutive patients with HAM/TSP from Sarah Salvador Unit of the Rehabilitation, in Bahia, Brazil. They were evaluated from September 2007 to July 2008. We used the following scales: Functional disability scales (EDSS, OSAME e HOFFER); visual analogue scale; Hospital Anxiety and Depression Scale; McGill Pain Questionnaire; DN4 Questionnaire and SF-36 Quality-of-Life Questionnaire.

Results: chronic pain was highly prevalent (38 patients---88.4%) in this population. We detected an inverse correlation between duration of the disease and the likelihood of patients to present with chronic pain (P<0.05). Individuals with greater neurologic deficits had much more neuropathic, whereas those with lower motor deficit had mainly the characteristics of nociceptive pain (P<0.05). A positive correlation was observed between the score of the dominant pain or the additional pain, and the number of pain descriptors (P<0.05 for both evaluations). The patients with chronic pain had worst Quality-of-Life scores (P<0.05).

Conclusion: chronic pain was significantly associated with a higher likelihood of signs/symptoms of anxiety and depression, reflecting a negative impact of pain on patients´ quality of life.

MeSH terms

  • Brazil / epidemiology
  • Chronic Disease
  • Comorbidity
  • Female
  • HTLV-I Infections / epidemiology*
  • HTLV-I Infections / psychology
  • Human T-lymphotropic virus 1*
  • Humans
  • Male
  • Middle Aged
  • Pain / diagnosis
  • Pain / epidemiology*
  • Pain / psychology
  • Paraparesis, Tropical Spastic / epidemiology*
  • Paraparesis, Tropical Spastic / psychology
  • Quality of Life*
  • Risk Assessment
  • Risk Factors
  • Surveys and Questionnaires