Meningoencephalitis caused by varicella-zoster virus reactivation in a child with dominant partial interferon-gamma receptor-1 deficiency

Pediatr Infect Dis J. 2011 Mar;30(3):265-6. doi: 10.1097/INF.0b013e3181f6f78a.

Abstract

We describe a previously symptom-free 13-year-old boy with dominant partial interferon-γ receptor-1 deficiency and unusual varicella-zoster virus reactivation. This case supports the unsettled notion that some interferon-γ R-deficient patients are at enhanced risk for viral disease.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Encephalitis, Varicella Zoster / diagnosis*
  • Encephalitis, Varicella Zoster / virology*
  • Herpesvirus 3, Human / isolation & purification*
  • Humans
  • Immunologic Deficiency Syndromes / complications*
  • Interferon gamma Receptor
  • Male
  • Meningoencephalitis / diagnosis*
  • Meningoencephalitis / virology*
  • Receptors, Interferon / deficiency*
  • Virus Activation

Substances

  • Receptors, Interferon