Effectiveness of measles vaccination for control of exposed children

Pediatr Infect Dis J. 2011 Jan;30(1):78-80. doi: 10.1097/INF.0b013e3181f7001c.

Abstract

The effectiveness of measles vaccine for postexposure prophylaxis at educational centers was investigated. A total of 166 children who shared the classroom with 10 confirmed cases during the infectious period of cases were studied. Of total susceptible exposed children, 72% (54/75) were vaccinated and 25 contracted measles. Vaccine effectiveness in children vaccinated within 72 hours of exposure was 90.5% (95% confidence interval, 34%-99%).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child Day Care Centers
  • Child, Preschool
  • Cohort Studies
  • Disease Outbreaks / prevention & control*
  • Humans
  • Infant
  • Measles / immunology
  • Measles / prevention & control*
  • Measles-Mumps-Rubella Vaccine / administration & dosage*
  • Measles-Mumps-Rubella Vaccine / immunology
  • Multivariate Analysis
  • Post-Exposure Prophylaxis / methods*
  • Retrospective Studies
  • Students
  • Time Factors

Substances

  • Measles-Mumps-Rubella Vaccine