Patients with vibration disease caused by local vibration and those with the disease caused by general vibration demonstrate similar changes in regulation of central nervous system, as shown by EEG--diffuse changes and locus of pathologic activity mostly in right temporal cortex. Unlike local vibration, the combined one acting long (over 10-15 years) causes more pathologic changes in brain, not only in cerebral cortex, but also in brainstem and diencephalic structures.