Abstract
Chronic graft-versus-host disease (cGVHD) is a multi-organ disease that occurs post-hematopoietic stem cell transplantation, with the mouth being one of the most frequently affected organs. In 2009, the German-Austrian-Swiss working party on bone marrow and blood stem cell transplantation held a consensus conference to define clinical management of cGVHD. The consensus conference aimed to summarize the literature on diagnosis and topical treatment options for oral cGVHD and to provide recommendations for clinical practice, including routine dental and oral care as well as monitoring for secondary malignancies and bisphophonate-induced osteonecrosis of the jaw.
Publication types
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Consensus Development Conference
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Practice Guideline
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Research Support, Non-U.S. Gov't
MeSH terms
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Administration, Topical
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Chronic Disease
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Dental Caries / etiology
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Evidence-Based Dentistry
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Glucocorticoids / administration & dosage
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Graft vs Host Disease / diagnosis*
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Graft vs Host Disease / drug therapy*
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Graft vs Host Disease / etiology
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Hematopoietic Stem Cell Transplantation / adverse effects*
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Humans
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Immunosuppressive Agents / administration & dosage
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Jaw Diseases / chemically induced
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Mouth Diseases / diagnosis
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Mouth Diseases / drug therapy*
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Mouth Diseases / etiology
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Mouth Neoplasms / etiology
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Neoplasms, Second Primary / etiology
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Oral Surgical Procedures / adverse effects*
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Osteonecrosis / chemically induced
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Periodontal Diseases / etiology
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Xerostomia / complications
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Xerostomia / drug therapy
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Xerostomia / etiology
Substances
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Glucocorticoids
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Immunosuppressive Agents