Emergence of fluoroquinolone-resistant Streptococcus pneumoniae in Lebanon: a report of three cases

J Infect Public Health. 2010;3(3):113-7. doi: 10.1016/j.jiph.2010.07.003. Epub 2010 Aug 24.

Abstract

The global emergence of Streptococcus pneumoniae resistance to fluoroquinolones is alarming and has grown to be a cause for significant concern worldwide. We report the first three cases of levofloxacin resistant S. pneumoniae isolates in a tertiary medical center in Beirut, Lebanon. Judicious use of antimicrobial agents is imperative to limit the spread of such resistant strains.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anti-Bacterial Agents / pharmacology*
  • Anti-Bacterial Agents / therapeutic use*
  • Cefepime
  • Ceftazidime / pharmacology
  • Ceftazidime / therapeutic use
  • Cephalosporins / pharmacology
  • Cephalosporins / therapeutic use
  • Clarithromycin / pharmacology
  • Clarithromycin / therapeutic use
  • Drug Resistance, Multiple, Bacterial*
  • Humans
  • Imipenem / pharmacology
  • Imipenem / therapeutic use
  • Lebanon
  • Levofloxacin*
  • Male
  • Ofloxacin / pharmacology*
  • Ofloxacin / therapeutic use*
  • Pneumococcal Infections / drug therapy*
  • Pneumococcal Infections / microbiology
  • Pneumonia, Pneumococcal / drug therapy*
  • Pneumonia, Pneumococcal / microbiology
  • Streptococcus pneumoniae / drug effects*
  • Vancomycin / pharmacology
  • Vancomycin / therapeutic use

Substances

  • Anti-Bacterial Agents
  • Cephalosporins
  • Levofloxacin
  • Vancomycin
  • Imipenem
  • Cefepime
  • Ceftazidime
  • Ofloxacin
  • Clarithromycin