[Acute cytomegalovirus infection revealing systemic lupus erythematosus]

W Hachfi; J-J Laurichesse; M-P Chauveheid; N Houhou; D Bonnet; P Longuet; C Leport

doi:10.1016/j.revmed.2010.03.456

[Acute cytomegalovirus infection revealing systemic lupus erythematosus]

Rev Med Interne. 2011 Jan;32(1):e6-8. doi: 10.1016/j.revmed.2010.03.456. Epub 2010 Sep 28.

[Article in French]

Authors

W Hachfi¹, J-J Laurichesse, M-P Chauveheid, N Houhou, D Bonnet, P Longuet, C Leport

Affiliation

¹ Laboratoire de recherche en pathologie infectieuse, université Diderot-Paris 7 site Bichat, 16 rue Henri-Huchard, Paris, France. [email protected]

PMID: 20880615
DOI: 10.1016/j.revmed.2010.03.456

Abstract

Systemic lupus erythematosus (SLE) remains of unknown origin. Herpes viridae infections seem to play a role in the pathogenesis of this disease. We report a 31-year-old man who presented an acute cytomegalovirus (CMV) infection with persistent fever and myopericarditis as the presenting manifestation of SLE. This case report emphasizes a difficult differential diagnosis between SLE and an acute CMV infection and suggests a possible role of this virus in the pathogenesis of SLE.

Publication types

Case Reports
English Abstract

MeSH terms

Acute Disease
Adult
Antimalarials / therapeutic use
Antirheumatic Agents / therapeutic use
Cytomegalovirus Infections / complications*
Cytomegalovirus Infections / diagnosis
Cytomegalovirus Infections / drug therapy
Cytomegalovirus* / isolation & purification
Cytomegalovirus* / pathogenicity
Diagnosis, Differential
Drug Therapy, Combination
Fever / virology
Glucocorticoids / therapeutic use
Humans
Lupus Erythematosus, Systemic / diagnosis*
Lupus Erythematosus, Systemic / drug therapy
Lupus Erythematosus, Systemic / virology*
Male
Myocarditis / virology
Pericarditis / virology
Treatment Outcome

Substances

Antimalarials
Antirheumatic Agents
Glucocorticoids