Vaccination coverage in Papum Pare district, Arunachal Pradesh was observed to be low. We evaluated the universal immunization programme (UIP) through survey of health facilities in the district and collected data about inputs and processes for childhood vaccination, cold-chain maintenance, supervision and monitoring. Using cluster sampling methodology, we selected 697 children aged 12-23 months from 41 clusters and interviewed their mothers to collect information about vaccination status, socio-demographic factors, knowledge, attitude and practices. Only 50% health facilities in the district were conducting fixed-day immunizations. Of the children surveyed, 55% were fully vaccinated. Mothers who were informed about next due date by health workers, possessed immunization card, attended antenatal clinics, or who delivered in hospital were likely to complete the vaccination schedule of their children. In order to increase the vaccination coverage, all health facilities in the district need to be made functional for conducting immunization. Educating health workers to remind mothers about due date of vaccination will also help increasing the vaccination coverage.