Combining independent drug classes into superior, synergistically acting hybrid molecules

Angew Chem Int Ed Engl. 2010 Nov 8;49(46):8743-6. doi: 10.1002/anie.201004437.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Amyloid beta-Peptides / chemistry*
  • Animals
  • CHO Cells
  • Cricetinae
  • Cricetulus
  • Drug Design
  • Humans
  • Immunoprecipitation
  • Oligopeptides / chemistry*
  • Oligopeptides / pharmacology
  • Protein Structure, Secondary
  • Pyrazoles / chemistry
  • Stereoisomerism

Substances

  • Amyloid beta-Peptides
  • D3 peptide
  • Oligopeptides
  • Pyrazoles
  • trimer-TEG-D3