The biological targets of acivicin inspired 3-chloro- and 3-bromodihydroisoxazole scaffolds

Chem Commun (Camb). 2010 Nov 28;46(44):8475-7. doi: 10.1039/c0cc02825h. Epub 2010 Oct 8.

Abstract

Target analysis of acivicin derived 3-halodihydroisoxazoles scaffolds in living non-pathogenic and pathogenic bacteria.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aldehyde Dehydrogenase / chemistry
  • Bacterial Proteins / chemistry
  • Isomerism
  • Isoxazoles / chemistry*
  • Oxazoles / chemical synthesis
  • Oxazoles / chemistry*
  • Staphylococcus aureus / enzymology

Substances

  • Bacterial Proteins
  • Isoxazoles
  • Oxazoles
  • Aldehyde Dehydrogenase
  • acivicin