Abstract
Primary electrical diseases or channelopathies are inherited genetic alterations of the cell ionic and electrical behavior leading to various cardiac arrhythmias carrying the risk of sudden death. A descriptive review of the successively described channelopathies is made in this article, with emphasis on the clinical manifestations, the genetic background and the currently accepted therapeutic options.
MeSH terms
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Channelopathies / diagnosis*
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Channelopathies / epidemiology
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Channelopathies / genetics
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Channelopathies / therapy*
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Death, Sudden, Cardiac
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Electrophysiology
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Humans
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Long QT Syndrome / diagnosis
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Long QT Syndrome / genetics
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Long QT Syndrome / therapy
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Risk Assessment
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Tachycardia, Ventricular / diagnosis
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Tachycardia, Ventricular / genetics
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Tachycardia, Ventricular / therapy
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Ventricular Fibrillation / diagnosis
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Ventricular Fibrillation / physiopathology
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Ventricular Fibrillation / therapy