Low bone turnover and increase of bone mineral density in a premenopausal woman with postoperative hypoparathyroidism and thyroxine suppressive therapy

K Amrein; H P Dimai; H Dobnig; A Fahrleitner-Pammer

doi:10.1007/s00198-010-1441-9

Low bone turnover and increase of bone mineral density in a premenopausal woman with postoperative hypoparathyroidism and thyroxine suppressive therapy

Osteoporos Int. 2011 Nov;22(11):2903-5. doi: 10.1007/s00198-010-1441-9. Epub 2010 Oct 20.

Authors

K Amrein¹, H P Dimai, H Dobnig, A Fahrleitner-Pammer

Affiliation

¹ Department of Internal Medicine, Division of Endocrinology and Metabolism, Medical University of Graz, Auenbruggerplatz 15, Graz, Austria. [email protected]

PMID: 20959964
DOI: 10.1007/s00198-010-1441-9

Abstract

We report the case of a 36-year-old woman who developed permanent hypoparathyroidism after thyroidectomy for differentiated thyroid carcinoma. A 6-year follow-up showed an increase of 11% in absolute bone mineral density at the spine and 6% at the hip accompanied by low bone turnover despite thyroid-stimulating hormone suppressive thyroxine therapy.

Publication types

Case Reports

MeSH terms

Absorptiometry, Photon
Adult
Antacids / therapeutic use
Bone Density / physiology*
Bone Density Conservation Agents / therapeutic use
Bone Remodeling / physiology*
Calcitriol / therapeutic use
Calcium Carbonate / therapeutic use
Female
Femur / diagnostic imaging*
Follow-Up Studies
Humans
Hypoparathyroidism / etiology*
Lumbar Vertebrae / diagnostic imaging*
Premenopause
Thyroid Neoplasms / surgery
Thyroidectomy / adverse effects*
Thyroxine / therapeutic use

Substances

Antacids
Bone Density Conservation Agents
Calcitriol
Calcium Carbonate
Thyroxine