Sacral neuromodulation in urological indications: the Finnish experience

Scand J Urol Nephrol. 2011 Feb;45(1):46-51. doi: 10.3109/00365599.2010.523013. Epub 2010 Oct 21.

Abstract

Objective: Sacral neuromodulation is a treatment modality for voiding dysfunction that is resistant to conventional medical and surgical treatments. In Finland, sacral neuromodulation has been used for the treatment of urgency-frequency syndrome, non-obstructive urinary retention and painful bladder/interstitial cystitis since 1996.

Material and methods: The investigation retrospectively evaluated 180 tested patients, 74 of whom underwent permanent implantation of the InterStim device.

Results: A positive test result leading to implantation was significantly more frequent among females than males. Among urinary retention patients, the patients with a positive test leading to implantation were significantly younger than those without implantation. The implantation operation time was significantly shorter when using a tined lead device compared with open electrode insertion (76 vs 122 min). The mean follow-up time was 41 months (range 0-143). Significant improvement after implantation was noted in the mean urinated volumes and number of daily urinations, as well as in the number of catheterizations in urgency-frequency syndrome and urinary retention, respectively. The subjective long-term outcome was similar in these indications. Surgical revision was required for 15 patients (20.3% of implanted patients).

Conclusions: The difference in gender distribution compared with earlier published series may be explained by a selection bias due to the limited referrals of female patients from gynaecologists. The results favour the use of a tined lead device because of the shorter operating room time. Furthermore, the outcome seems to be more favourable among patients with a staged implant procedure compared with a one-stage operation with a tined lead device.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Cystitis / physiopathology
  • Cystitis / therapy*
  • Electric Stimulation Therapy / instrumentation
  • Electric Stimulation Therapy / methods*
  • Electrodes, Implanted
  • Female
  • Finland
  • Follow-Up Studies
  • Humans
  • Lumbosacral Plexus / physiology*
  • Male
  • Middle Aged
  • Retrospective Studies
  • Treatment Outcome
  • Urinary Bladder, Overactive / physiopathology
  • Urinary Bladder, Overactive / therapy*
  • Urinary Incontinence, Urge / physiopathology
  • Urinary Incontinence, Urge / therapy*
  • Urinary Retention / physiopathology
  • Urinary Retention / therapy*
  • Urination / physiology
  • Urine / physiology
  • Young Adult