Discordance between fasting glucose-based and hemoglobin A1c-based diagnosis of diabetes mellitus in Koreans

Diabetes Res Clin Pract. 2011 Jan;91(1):e8-e10. doi: 10.1016/j.diabres.2010.09.025.

Abstract

We analyzed data of 35,624 non-diabetic Koreans using fasting plasma glucose (FPG) criteria and HbA1c criteria in screening for diabetes. Among the 1,491 subjects newly diagnosed with diabetes, 473 (31.6%) met the FPG criteria only (≥7.0mmol/l), 350 (23.5%) met HbA1c criteria only (≥6.5%), and 668 (44.9%) met both criteria. The DM-by-HbA1c group had significantly older age, higher proportion of women, and lower hemoglobin concentration. The DM-by-FPG group had higher systolic and diastolic blood pressure, fasting serum insulin, and HOMA-IR. Further studies are needed to determine which of these criteria is superior in predicting the risks of long-term vascular complications of diabetes.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Aging
  • Anemia / complications
  • Anemia / epidemiology
  • Blood Glucose / analysis*
  • Diabetes Complications / epidemiology
  • Diabetes Mellitus / blood*
  • Diabetes Mellitus / diagnosis*
  • Diabetes Mellitus / epidemiology
  • Female
  • Glycated Hemoglobin / analysis*
  • Humans
  • Hypertension / complications
  • Hypertension / epidemiology
  • Insulin Resistance
  • Male
  • Middle Aged
  • Prevalence
  • Preventive Health Services
  • Republic of Korea / epidemiology
  • Retrospective Studies
  • Sex Characteristics
  • Young Adult

Substances

  • Blood Glucose
  • Glycated Hemoglobin A
  • hemoglobin A1c protein, human