Chronic myelogenous leukemia following radiotherapy and chemotherapy for non-Hodgkin lymphoma

Haematologica. 1990 Sep-Oct;75(5):477-9.

Abstract

We report here a women who developed chronic myelogenous leukemia (CML) after successful radiotherapy and chemotherapy for non-Hodgkin lymphoma. Review of the literature indicates that exposure to ionizing radiation is associated with an increased risk of CML.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / adverse effects*
  • Colonic Neoplasms / drug therapy
  • Colonic Neoplasms / radiotherapy*
  • Combined Modality Therapy
  • Cyclophosphamide / administration & dosage
  • Cyclophosphamide / adverse effects
  • Female
  • Genes, abl / radiation effects
  • Humans
  • Laryngeal Neoplasms / radiotherapy*
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / chemically induced
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / etiology*
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / genetics
  • Middle Aged
  • Neoplasms, Multiple Primary*
  • Neoplasms, Radiation-Induced / etiology*
  • Oropharyngeal Neoplasms / radiotherapy*
  • Prednisone / administration & dosage
  • Prednisone / adverse effects
  • Vincristine / administration & dosage
  • Vincristine / adverse effects

Substances

  • Vincristine
  • Cyclophosphamide
  • Prednisone

Supplementary concepts

  • COP protocol 2