Novel variant form of t(11;22)(q23;q13)/MLL-EP300 fusion transcript in the evolution of an acute myeloid leukemia with myelodysplasia-related changes

Leuk Res. 2011 Mar;35(3):e18-20. doi: 10.1016/j.leukres.2010.09.024. Epub 2010 Oct 25.

Authors

Francois P Duhoux, Sigrid De Wilde, Geneviève Ameye, Khadija Bahloula, Sandrine Medves, Geoffrey Légé, Jeanne-Marie Libouton, Jean-Baptiste Demoulin, Hélène A Poirel

PMID: 20980053
DOI: 10.1016/j.leukres.2010.09.024

No abstract available

Publication types

Case Reports
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Aged
Chromosomes, Human, Pair 11 / genetics*
Chromosomes, Human, Pair 22 / genetics*
E1A-Associated p300 Protein / genetics
Genetic Variation / genetics*
Histone-Lysine N-Methyltransferase
Humans
Leukemia, Myeloid, Acute / complications
Leukemia, Myeloid, Acute / genetics*
Leukemia, Myeloid, Acute / pathology
Male
Myelodysplastic Syndromes / etiology*
Myelodysplastic Syndromes / pathology
Myelodysplastic Syndromes / therapy
Myeloid-Lymphoid Leukemia Protein / genetics
Oncogene Proteins, Fusion / genetics*
Translocation, Genetic / genetics*

Substances

KMT2A protein, human
Oncogene Proteins, Fusion
Myeloid-Lymphoid Leukemia Protein
Histone-Lysine N-Methyltransferase
E1A-Associated p300 Protein
EP300 protein, human