Abstract
A surveillance study to identify patients from the community with Escherichia coli resistant to broad-spectrum cephalosporins discovered two isolates that were also resistant to polymyxin B and colistin. One isolate from a patient in the community and a second from a patient who received multiple courses of polymyxin B also possessed a CTX-M-15 enzyme. Resistance to cationic peptides in E. coli is unusual, and testing for susceptibility to these agents should be performed.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Aged, 80 and over
-
Anti-Bacterial Agents / pharmacology*
-
Anti-Bacterial Agents / therapeutic use
-
Colistin / pharmacology
-
Escherichia coli / drug effects*
-
Escherichia coli / pathogenicity
-
Escherichia coli Infections / drug therapy
-
Escherichia coli Infections / microbiology
-
Female
-
Humans
-
Male
-
Microbial Sensitivity Tests
-
Middle Aged
-
Polymyxin B / pharmacology
-
Polymyxins / pharmacology*
Substances
-
Anti-Bacterial Agents
-
Polymyxins
-
Polymyxin B
-
Colistin