Factors associated with HIV-positive women carrying pregnancies to term

J Obstet Gynaecol Can. 2010 Aug;32(8):756-62. doi: 10.1016/s1701-2163(16)34616-3.

Abstract

Objectives: To determine predictors of HIV-positive women who choose to carry a pregnancy to term.

Methods: We collected pregnancy data up to December 2008 on women who had attended the University Health Network Immunodeficiency Clinic in Toronto since 2000 and were < 50 years of age at the time of their first HIV-positive test. Data were included on all pregnancies, including those that occurred before the woman was known to be HIV positive or first attended the clinic.

Results: Data were collected from a total of 341 women who were < 50 years of age at their first HIV-positive test. Of these women, 179 (52%) had a total of 484 pregnancies, and 110 of these pregnancies (23%) in 74 women were known to occur after the woman tested HIV positive. An additional 52 women (11%) were found to be HIV positive during the pregnancy. Predictors of a woman's carrying a pregnancy to term when HIV positive were age, region of maternal birth, number of previous live births, and pregnancy during the highly active antiretroviral therapy (HAART) era.

Conclusion: HIV-positive women are more likely to carry a pregnancy to term during the new HAART era than they were before this era. Younger African-born HIV-positive women who already have children are more likely than other HIV-positive women to choose to carry a pregnancy to term.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Cohort Studies
  • Female
  • HIV Seropositivity*
  • Humans
  • Pregnancy / statistics & numerical data*
  • Pregnancy Complications, Infectious*
  • Retrospective Studies
  • Term Birth*
  • Young Adult