Paraneoplastic myopathy as a very rare manifestation of acute lymphoblastic leukemia

Klin Padiatr. 2010 Nov;222(6):386-7. doi: 10.1055/s-0030-1265137. Epub 2010 Nov 5.

Abstract

We present a 9-year-old girl who developed acute muscular weakness of proximal muscles of the upper and lower limbs. Investigations revealed a common acute lymphoblastic leukemia. The neuromuscular symptoms are classified as a paraneoplastic neurological syndrome (PNS). Under chemotherapy according to ALL-BFM-2000 protocol symptoms resolved within 4 weeks. This case presents a rare manifestation of acute lymphoblastic manifestation.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Child
  • Diagnosis, Differential
  • Female
  • Humans
  • Muscle Weakness / diagnosis
  • Muscle Weakness / drug therapy
  • Neuromuscular Diseases / diagnosis*
  • Neuromuscular Diseases / drug therapy
  • Paraneoplastic Syndromes / diagnosis*
  • Paraneoplastic Syndromes / drug therapy
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / diagnosis*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy