Linkage of internal minisatellite loci on chromosome 1 and exclusion of autosomal dominant retinitis pigmentosa proximal to rhesus

C F Inglehearn; S S Papiha; M Jay; A F Wright; A T Moore; S S Bhattacharya

doi:10.1136/jmg.27.1.14

Linkage of internal minisatellite loci on chromosome 1 and exclusion of autosomal dominant retinitis pigmentosa proximal to rhesus

J Med Genet. 1990 Jan;27(1):14-6. doi: 10.1136/jmg.27.1.14.

Authors

C F Inglehearn¹, S S Papiha, M Jay, A F Wright, A T Moore, S S Bhattacharya

Affiliation

¹ Department of Human Genetics, University of Newcastle upon Tyne.

Abstract

We report the exclusion of a locus for autosomal dominant retinitis pigmentosa proximal to the rhesus locus in a single large pedigree. In addition, a previously unreported linkage is described between two chromosome 1 markers, which confirms that a highly variable minisatellite locus is placed internally on chromosome 1.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Chromosomes, Human, Pair 1*
DNA Probes
DNA, Satellite / genetics*
Genetic Linkage
Genetic Markers
Humans
Pedigree
Retinitis Pigmentosa / genetics*
Rh-Hr Blood-Group System / genetics

Substances

DNA Probes
DNA, Satellite
Genetic Markers
Rh-Hr Blood-Group System