SETting the clock for histone H4 monomethylation

Mol Cell. 2010 Nov 12;40(3):345-6. doi: 10.1016/j.molcel.2010.10.033.

Abstract

In this and a previous issue of Molecular Cell, Oda et al. (2010), Abbas et al. (2010), and Centore et al. (2010) determined that the H4K20 histone methyltransferase PR-Set7/Set8 is posttranslationally regulated by the PCNA-dependent CRL4(Cdt2) ubiquitin ligase.

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