High factor VIII activity, high plasminogen activator inhibitor 1 antigen levels and low factor XII activity contribute to a thrombophilic tendency in elderly venous thromboembolism patients

Acta Haematol. 2010;124(4):214-7. doi: 10.1159/000321530. Epub 2010 Nov 12.
No abstract available

MeSH terms

  • Age Factors
  • Aged
  • Factor V / genetics
  • Factor VIII / metabolism*
  • Factor XII / metabolism*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Mutation
  • Plasminogen Activator Inhibitor 1 / metabolism*
  • Point Mutation
  • Polymorphism, Single Nucleotide
  • Prothrombin / genetics
  • Venous Thromboembolism / blood
  • Venous Thromboembolism / epidemiology*
  • Venous Thromboembolism / genetics

Substances

  • Plasminogen Activator Inhibitor 1
  • factor V Leiden
  • Factor V
  • Prothrombin
  • Factor VIII
  • Factor XII