Abstract
The registry is an European, multicentre, prospective and longitudinal study which follows a cohort of children born to mothers with antiphospholipid syndrome (APS). In this article we report preliminary results obtained from 138 mothers and 141 babies (three twin pregnancies). At birth, 16.3% of neonates were less than 37 weeks of gestation and 17% were low birth weight; in addition, 11.3% of neonates were small for gestational age. No cases of neonatal thrombosis were observed. During follow-up period five children showed behavioral abnormalities. A long term clinical follow-up will be necessary to evaluate the neuropsychological development of these children.
MeSH terms
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Antibodies, Antiphospholipid / blood
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Antiphospholipid Syndrome / epidemiology*
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Autistic Disorder / epidemiology
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Autistic Disorder / etiology
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Child, Preschool
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Europe
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Female
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Follow-Up Studies
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Humans
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Immunity, Maternally-Acquired
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Infant
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Infant, Low Birth Weight
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Infant, Newborn
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Infant, Small for Gestational Age
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Infant, Very Low Birth Weight
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Learning Disabilities / epidemiology
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Learning Disabilities / etiology
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Pregnancy
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Pregnancy Complications / epidemiology*
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Pregnancy Outcome*
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Pregnancy, Multiple
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Premature Birth / epidemiology
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Prospective Studies
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Psychomotor Disorders / epidemiology
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Psychomotor Disorders / etiology
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Registries*
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Thrombosis / congenital
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Thrombosis / epidemiology
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Twins
Substances
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Antibodies, Antiphospholipid