Abstract
Porcine reproductive and respiratory syndrome virus (PRRSV) is a major swine pathogen causing economic losses in the swine industry almost worldwide. PRRSV has been divided into 2 genotypes, the European (Type 1) and North American (Type 2) genotype, respectively and displays a large degree of genetic variability, particularly at the nonstructural protein (nsp) 2 gene. This is the first study determining genetic variation of the nsp2 of Thai PRRSV isolates. The results showed that 9 out of 10 Thai PRRSV isolates were nsp2-truncated viruses that might have evolved from a virus previously introduced in the past, but not from one recently introduced.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Animals
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Genotype
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Molecular Sequence Data
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North America
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Polymorphism, Genetic*
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Porcine respiratory and reproductive syndrome virus / classification*
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Porcine respiratory and reproductive syndrome virus / genetics*
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Porcine respiratory and reproductive syndrome virus / isolation & purification
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RNA, Viral / genetics
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Sequence Alignment
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Sequence Analysis, DNA
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Swine
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Thailand
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Viral Nonstructural Proteins / genetics*
Substances
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RNA, Viral
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Viral Nonstructural Proteins
Associated data
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GENBANK/HM134182
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GENBANK/HM134183
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GENBANK/HM134184
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GENBANK/HM134185
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GENBANK/HM134186
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GENBANK/HM134187
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GENBANK/HM134188
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GENBANK/HM134189
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GENBANK/HM134190
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GENBANK/HM134191