Abstract
Several phenothiazines and related compounds were synthesized and their antifungal activity was evaluated in vitro. The results observed for α-chloro-N-acetyl phenothiazine led us to choose this compound as a lead in the search of antifungal agents.
Copyright © 2010 Elsevier Masson SAS. All rights reserved.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antifungal Agents / chemical synthesis*
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Antifungal Agents / chemistry
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Antifungal Agents / pharmacology*
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Drug Discovery
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Fungi / drug effects
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Microbial Sensitivity Tests
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Phenothiazines / chemical synthesis*
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Phenothiazines / chemistry
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Phenothiazines / pharmacology*
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Structure-Activity Relationship
Substances
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Antifungal Agents
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Phenothiazines
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phenothiazine