Fat tissue alters quadriceps response to femoral nerve magnetic stimulation

Clin Neurophysiol. 2011 Apr;122(4):842-7. doi: 10.1016/j.clinph.2010.10.028. Epub 2010 Nov 18.

Abstract

Objective: We investigate the influence that inguinal fat has on maximal quadriceps response to femoral nerve magnetic stimulation.

Methods: Vastus lateralis M-wave amplitude and quadriceps twitch peak torque were measured (i) in lean and overweight subjects and (ii) when slices of pig fat ranging from 2 to 18 mm in thickness were placed between the coil and the nerve.

Results: In overweight group, the maximal response could not be elicited when intensity was ≤90% and ≤85% of maximal power for twitch torque and M-wave amplitude, respectively. The maximal response was obtained at 80% of maximal power in the lean group. Negative correlations between relative twitch torque changes and inguinal thickness were observed. Fat thickness altered quadriceps response at 14 mm and 8 mm in the lean and overweight groups, respectively.

Conclusions: The capacity of femoral nerve magnetic stimulation to deliver supramaximal stimulation is altered when fat thickness below the coil increases.

Significance: Special caution should be taken by clinicians when overweight or obese subjects are tested using femoral nerve magnetic stimulation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adipose Tissue / physiology*
  • Adult
  • Body Composition / physiology
  • Data Interpretation, Statistical
  • Electromagnetic Fields
  • Electromyography
  • Femoral Nerve / physiology*
  • Humans
  • Isometric Contraction / physiology
  • Knee Joint / innervation
  • Knee Joint / physiology
  • Male
  • Muscle Contraction / physiology
  • Overweight / physiopathology
  • Quadriceps Muscle / physiology
  • Recruitment, Neurophysiological / physiology
  • Skinfold Thickness