Rapid recovery from panobinostat (LBH589)-induced thrombocytopenia in mice involves a rebound effect of bone marrow megakaryocytes

Leukemia. 2011 Feb;25(2):362-5. doi: 10.1038/leu.2010.262. Epub 2010 Nov 26.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Bone Marrow Cells
  • Cell Count
  • Histone Deacetylase Inhibitors
  • Hydroxamic Acids / toxicity*
  • Indoles
  • Kinetics
  • Megakaryocytes / cytology*
  • Mice
  • Mice, Inbred BALB C
  • Panobinostat
  • Thrombocytopenia / chemically induced*

Substances

  • Histone Deacetylase Inhibitors
  • Hydroxamic Acids
  • Indoles
  • Panobinostat