The evolving clinical scenario of myelodysplastic syndrome: the need for a complete and up to date upfront diagnostic assessment

Federica Pilo; Anna Angela Di Tucci; Paolo Dessalvi; Aldo Caddori; Emanuele Angelucci

doi:10.1016/j.ejim.2010.09.003

The evolving clinical scenario of myelodysplastic syndrome: the need for a complete and up to date upfront diagnostic assessment

Eur J Intern Med. 2010 Dec;21(6):490-5. doi: 10.1016/j.ejim.2010.09.003. Epub 2010 Oct 12.

Authors

Federica Pilo¹, Anna Angela Di Tucci, Paolo Dessalvi, Aldo Caddori, Emanuele Angelucci

Affiliation

¹ Hematology Unit, Ospedale Oncologico di riferimento Regionale Armando Businco Cagliari, Italy.

PMID: 21111932
DOI: 10.1016/j.ejim.2010.09.003

Abstract

Until the beginning of the current millennium, few concrete therapeutic possibilities were available for myelodysplastic syndrome (MDS) patients. This situation has dramatically changed in the last decade when new knowledge, new drugs and new opportunities have become available for physicians and their MDS patients. A correct diagnostic and prognostic assessment of all MDS patients wherever they are first seen in a hematology or internal medicine department is mandatory to identify the best therapeutic option and the most appropriate resources allocation. This article will review modern diagnostic criteria and classification together with correlated new therapeutic opportunities.

Publication types

Review

MeSH terms

Hematology / methods*
Hematology / trends*
Humans
Internal Medicine / methods*
Internal Medicine / trends*
Myelodysplastic Syndromes / diagnosis*
Myelodysplastic Syndromes / epidemiology
Myelodysplastic Syndromes / therapy
Prognosis
Risk Factors