Metal ion levels following resurfacing arthroplasty of the hip: serial results over a ten-year period

J Bone Joint Surg Br. 2010 Dec;92(12):1642-7. doi: 10.1302/0301-620X.92B12.24654.

Abstract

We report serum metal ion level data in patients with unilateral and bilateral hip resurfacing over a ten-year period. In these patients there is an increase in both cobalt and chromium levels above the accepted reference ranges during the first 18 months after operation. Metal ion levels remain elevated, but decline slowly for up to five years. However, the levels then appear to start rising again in some patients up to the ten-year mark. There was no significant difference in cobalt or chromium levels between men and women. These findings appear to differ from much of the current literature. The clinical significance of a raised metal ion level remains under investigation.

MeSH terms

  • Adult
  • Aged
  • Arthroplasty, Replacement, Hip / methods*
  • Chromium / blood*
  • Cobalt / blood*
  • Female
  • Follow-Up Studies
  • Hip Prosthesis
  • Humans
  • Male
  • Middle Aged
  • Postoperative Period
  • Prospective Studies

Substances

  • Chromium
  • Cobalt