This is a case of late-onset radial nerve palsy associated with the nonunion of the humeral shaft. Nonunion formation was caused by insufficient osteosynthesis and lack of proper biomechanical conditions for fracture healing. A good final outcome was achieved by simultaneous surgical treatment both nonunion of the humerus and radial nerve palsy. Radial nerve palsy presenting without delay after trauma or after reduction is well known complication of the humeral fracture. Case of late-onset palsy is very rare.