A new dimeric aporphine from the roots of Artabotrys spinosus

Jirapast Sichaem; Thanatip Ruksilp; Wisuttaya Worawalai; Pongpan Siripong; Suttira Khumkratok; Santi Tip-pyang

doi:10.1016/j.fitote.2010.11.025

A new dimeric aporphine from the roots of Artabotrys spinosus

Fitoterapia. 2011 Apr;82(3):422-5. doi: 10.1016/j.fitote.2010.11.025. Epub 2010 Dec 1.

Authors

Jirapast Sichaem¹, Thanatip Ruksilp, Wisuttaya Worawalai, Pongpan Siripong, Suttira Khumkratok, Santi Tip-pyang

Affiliation

¹ Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand.

PMID: 21130146
DOI: 10.1016/j.fitote.2010.11.025

Abstract

A new dimeric aporphine, artabotrysine along with five known compounds was isolated from the roots of Artabotrys spinosus. Their structures were fully established on the basis of spectral evidence. All isolated compounds were evaluated for their cytotoxicity on HeLa and KB cells.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Annonaceae / chemistry*
Aporphines / chemistry
Aporphines / isolation & purification*
Aporphines / pharmacology
HeLa Cells
Humans
KB Cells
Molecular Structure
Plant Extracts / chemistry*
Plant Extracts / pharmacology
Plant Roots

Substances

Aporphines
Plant Extracts
artabotrysine