[The genetic transfer, heredity and phenotypic expression of plasmid RP4::Mu cts genes in Bacillus cereus]

Biull Eksp Biol Med. 1990 Mar;109(3):299-301.
[Article in Russian]

Abstract

The transcipients were obtained in intrageneric matings of E.coli donor harbouring the plasmid PR4::Mu cts 62 with Bac. cereus GP7 recipient cells with the frequency 10(-9). The transcipient clone Bac. cereus 682 was selected having stably inherited and expressed the hybrid plasmid PR4::Mu cts 62 genes for antibiotic resistance and temperature sensitivity. Production of the bacteriophage Mu cts 62 particles was not registered in the bacillary transcipient cells. The plasmid RP4::Mu cts 62 genes were localized in the chromosome of Bac. cereus 682 transcipient by the blot-hybridization technique with 32P-labelled DNA of the bacteriophage Mu cts 62 and the plasmid PR4. The transcipient of Bac. cereus 682 has the donor properties and transfers the RP4::Mu cts 62 genes to recipient cells of Bac. cereus DSM 318 with the frequency of 10(-6)-10(-7). The expression and transfer of the gram-negative plasmid genes in gram-positive bacterial cells are discussed.

MeSH terms

  • Bacillus cereus / genetics*
  • Escherichia coli / genetics
  • Gene Expression Regulation, Bacterial / genetics*
  • Genes, Bacterial / genetics*
  • Genetic Markers
  • Phenotype
  • Plasmids / genetics*
  • Species Specificity
  • Transformation, Bacterial*

Substances

  • Genetic Markers