A systematic evaluation and validation of subtypes of adolescent alcohol use motives: genetic and environmental contributions

Alcohol Clin Exp Res. 2011 Mar;35(3):420-30. doi: 10.1111/j.1530-0277.2010.01359.x. Epub 2010 Dec 8.

Abstract

Background: Alcohol use motives are closely associated with specific profiles of alcohol use and reflect a subjectively derived decisional framework based on a motivational style of responding. Adult twin studies typically estimate the heritability of alcohol use motives to be between 7 and 42%, although relatively little is known about genetic and environmental influences upon alcohol use motives in adolescence.

Methods: Latent class analysis (LCA) models containing 1 through 5 classes were fitted to the data derived from 1,422 adolescent twin and siblings self-reported alcohol use motives. Using twin models, we estimated the genetic, shared, and nonshared environmental influences to the class membership data derived from the LCA.

Results: Four drinking motives classes were identified (family-oriented, social, enhancement/social, and coping/social). The coping/social and enhancement/social classes were differentiated from the social class on measures of depression, delinquency, and aggressive behavior. Analyses indicated that nonadditive genetic factors accounted for 76% of the variance in the coping/social motives class and additive genetic influences accounted for 66% of the variance in the social motives class. There was a moderate contribution of genetic factors and shared environmental factors influencing class membership of enhancement/social motivated drinkers (28 and 20% explained variance, respectively). Substantial shared environmental influences were revealed for membership of the family-oriented class (75%).

Conclusions: Heritable influences may predispose individuals to drink to cope with negative affect, for social reasons, and to a lesser extent for enhancement. Familial environmental influences shape family-oriented motives for drinking in adolescents.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Twin Study
  • Validation Study

MeSH terms

  • Adaptation, Psychological / physiology
  • Adolescent
  • Adolescent Behavior / physiology
  • Adolescent Behavior / psychology*
  • Age Factors
  • Alcohol Drinking / epidemiology
  • Alcohol Drinking / genetics*
  • Alcohol Drinking / psychology*
  • Child
  • Family
  • Female
  • Humans
  • Male
  • Motivation / genetics*
  • Random Allocation
  • Self Report
  • Social Environment*
  • Young Adult