Primary cilia bend LKB1 and mTOR to their will

Nicolas Aznar; Marc Billaud

doi:10.1016/j.devcel.2010.11.016

Primary cilia bend LKB1 and mTOR to their will

Dev Cell. 2010 Dec 14;19(6):792-4. doi: 10.1016/j.devcel.2010.11.016.

Authors

Nicolas Aznar¹, Marc Billaud

Affiliation

¹ UMR CNRS Molecular Genetics, Signaling and Cancer, Université Lyon, Centre Léon Bérard, France.

PMID: 21145495
DOI: 10.1016/j.devcel.2010.11.016

Abstract

Primary cilia are cell surface organelles that act as sensory antennae for various input signals. In a recent issue of Nature Cell Biology, Boehlke et al. (2010) demonstrate that bending of cilia regulates cell size through a signaling pathway involving the LKB1 and mTOR kinases.

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