A malignant oligarchy: progenitors govern the behavior of oligodendrogliomas

Cancer Cell. 2010 Dec 14;18(6):546-7. doi: 10.1016/j.ccr.2010.11.031.

Abstract

Recent studies have suggested that brain tumors arise from neural stem cells and are maintained by stem-like tumor-initiating cells (TICs). In this issue of Cancer Cell, Persson et al. report that oligodendrogliomas, unlike malignant astrocytomas, originate from-and are propagated by-cells that resemble oligodendrocyte progenitors.

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