Randomized controlled trial of ultrasonic dissection versus standard surgical technique in open left hemicolectomy or total gastrectomy

Br J Surg. 2011 Feb;98(2):220-7. doi: 10.1002/bjs.7354.

Abstract

Background: Ultrasonic dissection devices have been designed for use in open surgery but it is not certain how they compare with standard surgical techniques.

Methods: This was a multicentre randomized controlled trial comparing ultrasonic dissection with the traditional surgical technique for haemostasis and dissection during left hemicolectomy and total gastrectomy. The primary endpoint was duration of operation; secondary endpoints were blood loss and other intraoperative parameters, and patient outcomes. Performance of the two techniques was rated by surgeons and assistants on a ten-point Likert scale.

Results: The analysis included 100 patients in the ultrasonic and 101 in the conventional dissection group. Patient demographics, and clinical and tumour-related parameters were similar in the two groups. There was no significant difference in duration of operation (mean 170 and 178 min in ultrasonic and conventional groups respectively; P = 0·405). Nor were there significant differences in intraoperative blood loss (median 350 and 400 ml respectively; P = 0·882), other intraoperative parameters, oncological or functional outcome. The ultrasonic dissector device was rated one point higher than conventional techniques by the surgeons.

Conclusion: Use of the ultrasonic dissector in open total gastrectomy and hemicolectomy had no impact on the overall operating time or other endpoints studied. Surgeons preferred the ultrasonic device for dissection.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Blood Loss, Surgical
  • Colectomy / methods*
  • Dissection / methods*
  • Female
  • Gastrectomy / methods*
  • Humans
  • Male
  • Observer Variation
  • Quality of Life
  • Treatment Outcome
  • Ultrasonic Therapy / methods*

Associated data

  • ISRCTN/ISRCTN97779420