Functional, star polymeric molecular carriers, built from biodegradable microgel/nanogel cores

Chem Commun (Camb). 2011 Feb 7;47(5):1449-51. doi: 10.1039/c0cc04532b. Epub 2010 Dec 23.

Abstract

Acid and disulfide biodegradable cross-linkers have been employed to generate microgel star polymers, using RAFT-polymer arms. RAFT end-groups were then exploited to attach functional compounds via both thiol-ene and thiol-pyridyl disulfide exchange reactions.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Disulfides / chemistry*
  • Disulfides / metabolism
  • Hydrogen-Ion Concentration
  • Nanogels
  • Polyethylene Glycols / chemistry*
  • Polyethyleneimine / chemistry*
  • Polymers / chemistry*
  • Polymers / metabolism
  • Sulfhydryl Compounds / chemistry*
  • Sulfhydryl Compounds / metabolism

Substances

  • Disulfides
  • Nanogels
  • Polymers
  • Sulfhydryl Compounds
  • polyethylene glycol polyethyleneimine nanogel
  • Polyethylene Glycols
  • Polyethyleneimine