Successful treatment of chronic mucocutaneous candidiasis caused by azole-resistant Candida albicans with posaconazole

Clin Dev Immunol. 2011:2011:283239. doi: 10.1155/2011/283239. Epub 2010 Dec 1.

Abstract

Refractory or recurrent infections of skin, nails, and the mucous membranes are clinical signs of chronic mucocutaneous candidiasis, frequently associated with immunological defects. Here we describe a 39-years-old female patient, with familial CMC, that presented with an extensive infection caused by an azole-resistant Candida albicans isolate, successfully treated with posaconazole.

Publication types

  • Case Reports

MeSH terms

  • Administration, Oral
  • Adult
  • Antifungal Agents / therapeutic use
  • Candida albicans / pathogenicity
  • Candidiasis, Chronic Mucocutaneous* / drug therapy
  • Candidiasis, Chronic Mucocutaneous* / immunology
  • Drug Resistance, Fungal
  • Female
  • Humans
  • Treatment Outcome
  • Triazoles* / administration & dosage
  • Triazoles* / therapeutic use

Substances

  • Antifungal Agents
  • Triazoles
  • posaconazole