Long-term mortality and pacing outcomes of patients with permanent pacemaker implantation after cardiac surgery

Pacing Clin Electrophysiol. 2011 Mar;34(3):331-8. doi: 10.1111/j.1540-8159.2010.02972.x. Epub 2011 Jan 5.

Abstract

Background: Approximately 20,000 permanent pacemakers (PPMs) are implanted annually for bradycardia or atrioventricular (AV) block after cardiac surgery. Little is known about the long-term pacing and mortality outcomes and the temporal trends of these patients.

Methods: We examined 6,268 consecutive patients who underwent cardiac surgery at the Minneapolis Veterans Administration Medical Center between 1987 and 2010. Patients who had a PPM within 30 days of cardiac surgery were identified. Pacemaker interrogation records were retrospectively reviewed and mortality was ascertained.

Results: Overall, 141 (2.2%) patients underwent PPM implantation for high-degree AV block (55%) and bradycardia (45%), 9 ± 6 days after surgery. Age, diuretic use, cardiopulmonary bypass time (CPBT), and valve surgery were independent predictors of PPM requirement. After 5.6 ± 4.2 years of follow-up, 40% of the patients were PPM dependent. Longer CPBT (P = 0.03), PR interval >200 ms (P = 0.03), and QRS interval > 120 ms (P = 0.04) on baseline electrocardiogram predicted PPM dependency . In univariable analysis, PPM patients had a higher long-term mortality than those without PPM (45% vs 36%; P = 0.02). However, after adjusting for age, sex, type of surgery, and CPBT, PPM requirement was not associated with long-term mortality (hazard ratio 1.3; 95% confidence interval 0.9-1.9; P = 0.17). Compared to before, incidence of PPM implantation increased after the year 2000 (1.9% vs 2.6%; P = 0.04).

Conclusion: The majority of patients who require PPM after cardiac surgery are not PPM dependent in the long term. Requiring a PPM after surgery is not associated with long-term mortality after adjustment for patient-related risk factors and cardiac surgical procedure.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Aged
  • Cardiac Pacing, Artificial / mortality*
  • Cardiovascular Surgical Procedures / mortality*
  • Combined Modality Therapy
  • Equipment Safety
  • Female
  • Humans
  • Italy / epidemiology
  • Longitudinal Studies
  • Male
  • Pacemaker, Artificial / statistics & numerical data*
  • Prevalence
  • Prosthesis Implantation / mortality*
  • Risk Assessment
  • Risk Factors
  • Survival Analysis
  • Survival Rate
  • Treatment Outcome
  • United States / epidemiology