Peritoneal surface malignancies and regional treatment: a review of the literature

Matthew S Rubino; Raafat Z Abdel-Misih; Joseph J Bennett; Nicholas J Petrelli

doi:10.1016/j.suronc.2010.12.001

Peritoneal surface malignancies and regional treatment: a review of the literature

Surg Oncol. 2012 Jun;21(2):87-94. doi: 10.1016/j.suronc.2010.12.001. Epub 2011 Jan 8.

Authors

Matthew S Rubino¹, Raafat Z Abdel-Misih, Joseph J Bennett, Nicholas J Petrelli

Affiliation

¹ Department of Surgery, Helen F. Graham Cancer Center at Christiana Care, 4745 Ogletown-Stanton Road, Newark, DE 19713, USA. [email protected]

PMID: 21216590
DOI: 10.1016/j.suronc.2010.12.001

Abstract

Recent studies have lead to a renewed interest in cytoreductive surgery and intraperitoneal chemotherapy as a regional treatment modality for patients with peritoneal surface malignancies. There have been multiple phase III randomized trials that have shown a survival advantage with intraperitoneal chemotherapy in certain patients. More well designed phase III studies are needed to further define which groups of patients may benefit from cytoreductive surgery and intraperitoneal chemotherapy.

Publication types

Review

MeSH terms

Antineoplastic Agents / administration & dosage
Chemotherapy, Cancer, Regional Perfusion / methods*
Colorectal Neoplasms / drug therapy
Colorectal Neoplasms / surgery
Combined Modality Therapy / methods
Female
Humans
Hyperthermia, Induced / methods
Ovarian Neoplasms / drug therapy
Ovarian Neoplasms / surgery
Perioperative Care / methods
Peritoneal Neoplasms / drug therapy*
Peritoneal Neoplasms / surgery
Pseudomyxoma Peritonei / drug therapy
Pseudomyxoma Peritonei / surgery
Stomach Neoplasms / drug therapy
Stomach Neoplasms / surgery

Substances

Antineoplastic Agents